In-Plane Shear Strength of Single-Lap Co-Cured Joints of Self-Reinforced

Synthesis of novel polymeric nanoparticles (methoxy-polyethylene glycol-chitosan/hyaluronic acid) containing 7-ethyl-10-hydroxycamptothecin for colon most cancers remedy: in vitro, ex vivo and in vivo investigation

 The purpose of the present research was to focus on 7-ethyl-10-hydroxycamptothecin (SN38) orally to colon tumours by synthesizing a concentrating on polymer. To attain the optimum supply for SN38, initially methoxy-polyethylene glycol (mPEG)-chitosan was synthesized after which nanoparticles had been developed by means of ionic gelation between mPEG-chitosan and hyaluronic acid as a ligand for cell-surface glycoprotein CD44 receptor. The SN38 was loaded in nanoparticles (SN38-NPs) utilizing the non-covalent bodily adsorption methodology. The dimensions of the optimized SN38-NPs was 226.7 nm, encapsulation effectivity was 89.23% and drug content material was 7.98 ± 0.54% within the optimum formulation. The attachment of mPEG to chitosan was confirmed by proton nuclear magnetic resonance.

The outcomes of differential scanning calorimetry and Fourier transforms infra-red evaluation indicated that SN38 existed in amorphous type and purposeful teams of SN38 protected within the formulations which could possibly be an indication of appropriate encapsulation of SN38 in SN38-NPs. In vitro research indicated that SN38-NPs had been stronger towards the most cancers cells than free SN38. The mobile uptake of SN38-NPs improved as much as 1.6-fold towards human colorectal adenocarcinoma (Caco-2) cells. Furthermore, SN38-NPs remarkably demonstrated superior anti-tumor efficacy in opposite to pure SN38. This implies the benefit of SN38-NPs as a potent oral drug service which could possibly be additional explored for medical investigations.

In-Aircraft Shear Power of Single-Lap Co-Cured Joints of Self-Strengthened Polyethylene Composites

The current research introduces the evaluation of single-lap co-cured joints of thermoplastic self-reinforced composites made with reprocessed low-density polyethylene (LDPE) and bolstered by ultra-high-molecular-weight polyethylene (UHMWPE) fibers, together with a micromechanical evaluation of its constituents. A set of optimum processing circumstances for manufacturing these joints by hot-press is proposed by means of a design of experiment utilizing the response floor methodology to maximise their in-plane shear energy by carrying tensile checks on co-cured tapes.

Optimum processing circumstances had been discovered at 1 bar, 115 °C, and 300 s, yielding joints with 6.88 MPa of shear energy. The shear failure is usually preceded by a number of debonding-induced longitudinal cracks each inside and out of doors the joint because of accrued transversal stress. This composite demonstrated to be an fascinating structural materials to be extra extensively utilized in business, possessing extraordinarily elevated particular mechanical properties, progressive harm of co-cured joints (thus avoiding unannounced catastrophic failures) and supreme recyclability.

Synthesis, Properties, and Derivatization of Poly(dihydrogermane): A Germanium-Based mostly Polyethylene Analogue

 Polygermanes are germanium-based analogues of polyolefins and possess polymer backbones made up catenated Ge atoms. Within the current contribution we report the preparation of a germanium polyethylene analogue, polydihydrogermane (GeH2)n, through two easy approaches that contain topotactic deintercalation of Ca ions from the CaGe Zintl section.

The ensuing (GeH2)n possesses morphologically dependent chemical and digital properties and thermally decomposes to yield amorphous hydrogenated Ge. We additionally present that the ensuing (GeH2)n offers a platform from which functionalized polygermanes might be ready through thermally induced hydrogermylation-mediated pendant group substitution.

albright-wilson
albright-wilson

PEG Antibody / Polyethylene Glycol

R20194BTN-50UG 50ug
EUR 489

Polyethylene Glycol (PEG) CLIA Kit

20-abx490560
  • EUR 11090.40
  • EUR 5904.00
  • EUR 1356.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-10x96wellstestplate 10x96-wells test plate
EUR 7248.6
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-1x48wellstestplate 1x48-wells test plate
EUR 702.12
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-1x96wellstestplate 1x96-wells test plate
EUR 951.6
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

CEX163Ge-5x96wellstestplate 5x96-wells test plate
EUR 3922.2
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Polyethylene Glycol (PEG) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Polyethylene Glycol (PEG) ELISA Kit

4-CEX163Ge
  • EUR 7309.20
  • EUR 3862.80
  • EUR 952.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Polyethylene Glycol (PEG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

General Polyethylene Glycol ELISA Kit (PEG)

RK00701 96 Tests
EUR 687.6

BSA Conjugated Polyethylene Glycol (PEG)

4-CPX163Ge11
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pan-species Polyethylene Glycol expressed in: E.coli

OVA Conjugated Polyethylene Glycol (PEG)

4-CPX163Ge21
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pan-species Polyethylene Glycol expressed in: E.coli

Polyethylene Glycol (PEG) Antibody (Biotin)

abx021052-005mg 0.05 mg
EUR 978

Polyethylene Glycol (PEG) Protein (BSA)

20-abx651925
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Polyethylene Glycol (PEG) Protein (OVA)

20-abx651926
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

ELISA kit for General PEG (Polyethylene Glycol)

ELK8264 1 plate of 96 wells
EUR 446.4
Description: A competitive Inhibition ELISA kit for detection of Polyethylene Glycol from General in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species)

4-PAX163Ge01
  • EUR 303.60
  • EUR 3138.00
  • EUR 778.80
  • EUR 382.80
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG)

Polyethylene glycol 1500

GK2627-100G 100 g
EUR 52.8

Polyethylene glycol 1500

GK2627-1KG 1 kg
EUR 74.4

Polyethylene glycol 1500

GK2627-500G 500 g
EUR 58.8

Polyethylene glycol 1000

GC0081-100G 100 g
EUR 55.2

Polyethylene glycol 8000

GC0902-100G 100 g
EUR 57.6

Polyethylene glycol 8000

GC0902-1KG 1 kg
EUR 92.4

Polyethylene glycol 8000

GC0902-500G 500 g
EUR 74.4

Polyethylene glycol 6000

GC2342-100G 100 g
EUR 52.8

Polyethylene glycol 6000

GC2342-1KG 1 kg
EUR 74.4

Polyethylene glycol 6000

GC2342-500G 500 g
EUR 58.8

Polyethylene glycol 400

GC3481-100G 100 g
EUR 49.2

Polyethylene glycol 400

GC3481-1KG 1 kg
EUR 78

Polyethylene glycol 400

GC3481-250G 250 g
EUR 55.2

Polyethylene glycol 400

GC3481-500G 500 g
EUR 63.6

Polyethylene glycol 400

GC3481-5KG 5 kg
EUR 183.6

Polyethylene glycol 300

GC9998-100G 100 g
EUR 48

Polyethylene glycol 300

GC9998-1KG 1 kg
EUR 74.4

Polyethylene glycol 300

GC9998-250G 250 g
EUR 52.8

Polyethylene glycol 300

GC9998-500G 500 g
EUR 62.4

Polyethylene glycol 300

GC9998-5KG 5 kg
EUR 170.4

Polyethylene glycol 4000

GX6931-100G 100 g
EUR 52.8

Polyethylene glycol 4000

GX6931-1KG 1 kg
EUR 74.4

Polyethylene glycol 4000

GX6931-500G 500 g
EUR 58.8

Polyethylene Glycol - 200

S-3126 1ML
EUR 38.76

Polyethylene Glycol - 400

S-3127 1ML
EUR 77.52

Polyethylene Glycol - 600

S-3128 1ML
EUR 38.76

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), APC

4-PAX163Ge01-APC
  • EUR 426.00
  • EUR 4102.80
  • EUR 1137.60
  • EUR 544.80
  • EUR 268.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with APC.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), Biotinylated

4-PAX163Ge01-Biotin
  • EUR 381.60
  • EUR 3078.00
  • EUR 903.60
  • EUR 469.20
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with Biotin.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), Cy3

4-PAX163Ge01-Cy3
  • EUR 518.40
  • EUR 5420.40
  • EUR 1467.60
  • EUR 676.80
  • EUR 308.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with Cy3.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), FITC

4-PAX163Ge01-FITC
  • EUR 364.80
  • EUR 3306.00
  • EUR 933.60
  • EUR 459.60
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with FITC.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), HRP

4-PAX163Ge01-HRP
  • EUR 388.80
  • EUR 3574.80
  • EUR 1005.60
  • EUR 492.00
  • EUR 252.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with HRP.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), PE

4-PAX163Ge01-PE
  • EUR 364.80
  • EUR 3306.00
  • EUR 933.60
  • EUR 459.60
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with PE.

Polyethylene Glycol (PEG) Polyclonal Antibody (Pan-species), APC-Cy7

4-PAX163Ge01-APC-Cy7
  • EUR 708.00
  • EUR 8061.60
  • EUR 2132.40
  • EUR 945.60
  • EUR 393.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pan-species Polyethylene Glycol (PEG). This antibody is labeled with APC-Cy7.

Mouse Anti-PEG mAb [Anti-Polyethylene glycol monoclonal antibody]

57000 50 ug
EUR 199

HSP70 ELISA Kit (High-Sensitivity)

EK7109 96wells/kit, with removable strips.
EUR 909.6

HSP70 ELISA Kit (High-Sensitivity)

abx259904-96well 96 well
EUR 1299.6

HSP70 ELISA Kit (High-Sensitivity)

SKT-108-480 5 plates of 96 wells
EUR 3242.4
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

HSP70 ELISA Kit (High-Sensitivity)

SKT-108-96 1 plate of 96 wells
EUR 822
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

D-alpha-Tocopherol polyethylene glycol succinate

GK2339-25G 25 g
EUR 180

D-alpha-Tocopherol polyethylene glycol succinate

GK2339-5G 5 g
EUR 84

OVAL High Sensitivity ELISA Kit (OKCD01353)

OKCD01353 96 Wells
EUR 715.2
Description: Description of target: Non-inhibitory serpin. Storage protein of egg white.;Species reactivity: pan-species;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: <28 pg/mL

Human EGF ELISA Kit (High Sensitivity)

RK00024HS 96 Tests
EUR 704.4

Human Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-010 1 Kit
EUR 854.4

Human Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-020 1 Kit
EUR 854.4

Mouse Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-030 1 Kit
EUR 854.4

Mouse Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-040 1 Kit
EUR 854.4

Monkey Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-050 1 Kit
EUR 854.4

Monkey Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-060 1 Kit
EUR 854.4

Rat Anti-PEG IgG ELISA Kit, 96 tests, Quantitative

PEG-070 1 Kit
EUR 854.4

Rat Anti-PEG IgM ELISA Kit, 96 tests, Quantitative

PEG-080 1 Kit
EUR 854.4

ChromaFlash High-Sensitivity ChIP Kit  

P-2027-24 24 Reactions
EUR 338.8

ChromaFlash High-Sensitivity ChIP Kit  

P-2027-48 48 Reactions
EUR 512.6

ChromaFlash High-Sensitivity ChIP Kit  

P-2027
  • EUR 771.66
  • EUR 338.80
  • EUR 512.60
  • 48 Reactions
  • 24 Reactions
  • 48 Reactions

Poly(ethylene glycol) methyl ether (mPEG) Molecular Weight: 20000

PEG-20K 100 mg
EUR 270

Morphine antibody (High Sensitivity)

10-1379 1 mg
EUR 202.8
Description: Mouse monoclonal Morphine antibody

TMB Precipitating (High Sensitivity)

TM5125 125 ml
EUR 102

TMB Precipitating (High Sensitivity)

TM5500 500 ml
EUR 165.6

TMB Precipitating (High Sensitivity)

TM5999 1000 ml
EUR 249.6

High-Sensitivity Plate Spreader

FSA1030 PK2
EUR 17.4

High-sensitivity Human Growth Hormone ELISA Kit

DEIA449 96T
EUR 814.8
Description: Thishigh-sensitivity Human Growth Hormone ELISA Kit is to be used for the invitro quantitative determination of human growth hormone (hGH) concentrationsin serum.

Rat High Sensitivity Insulin (INS) ELISA Kit

abx363835-96tests 96 tests
EUR 943.2

IGF1 High Sensitivity ELISA Kit (Dog) (OKCD01300)

OKCD01300 96 Wells
EUR 1123.2
Description: Description of target: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca2+-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.;Species reactivity: Dog;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.5 pg/mL

Il10 High Sensitivity ELISA Kit (Mouse) (OKCD01301)

OKCD01301 96 Wells
EUR 1044
Description: Description of target: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.43 pg/mL

Il1a High Sensitivity ELISA Kit (Mouse) (OKCD01303)

OKCD01303 96 Wells
EUR 1090.8
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.03 pg/mL

Il1a High Sensitivity ELISA Kit (Rat) (OKCD01304)

OKCD01304 96 Wells
EUR 888
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.8 pg/mL

IL2 High Sensitivity ELISA Kit (Human) (OKCD01305)

OKCD01305 96 Wells
EUR 856.8
Description: Description of target: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.51 pg/mL

IL6 High Sensitivity ELISA Kit (Bovine) (OKCD01306)

OKCD01306 96 Wells
EUR 1123.2
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.45 pg/mL

IL6 High Sensitivity ELISA Kit (Goat) (OKCD01307)

OKCD01307 96 Wells
EUR 1248
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Goat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.138 pg/mL

IL6 High Sensitivity ELISA Kit (Human) (OKCD01308)

OKCD01308 96 Wells
EUR 777.6
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.35 pg/mL

IL6 High Sensitivity ELISA Kit (Sheep) (OKCD01309)

OKCD01309 96 Wells
EUR 1232.4
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Sheep;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.46 pg/mL

Il6 High Sensitivity ELISA Kit (Rat) (OKCD01310)

OKCD01310 96 Wells
EUR 730.8
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.47 pg/mL

IL8 High Sensitivity ELISA Kit (Human) (OKCD01311)

OKCD01311 96 Wells
EUR 777.6
Description: Description of target: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.7 pg/mL

LN High Sensitivity ELISA Kit (Human) (OKCD01312)

OKCD01312 96 Wells
EUR 997.2
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

MMP1 High Sensitivity ELISA Kit (Rabbit) (OKCD01313)

OKCD01313 96 Wells
EUR 1075.2
Description: Description of target: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. ;Species reactivity: Rabbit;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

MMP13 High Sensitivity ELISA Kit (Human) (OKCD01314)

OKCD01314 96 Wells
EUR 997.2
Description: Description of target: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.1;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 12.1 pg/mL

Coarse grained simulation of the aggregation and construction management of polyethylene nanocrystals

 Polyethylene (PE) telechelics with carboxylate purposeful teams at each ends have been proven to assemble into hexagonal nanocrystal platelets with a peak outlined by their chain size in primary CsOH-solution. On this coarse grained (CG) simulation research we present how properties of the purposeful teams alter the aggregation and crystallization conduct of these telechelics.

Systematic variation of the parameters of the CG mannequin confirmed that vital components which management nanoparticle stability and construction are the PE chain size and the hydrophilicity and the steric demand of the pinnacle teams.

To characterize the aggregation course of we analyzed the quantity and measurement of the obtained aggregates in addition to intramolecular order and intermolecular alignment of the polymer chains. By comparability of CG and atomistic simulation information, it could possibly be proven that atomistic simulations representing totally different chemical programs might be emulated with particular, totally different CG parameter units.

Thus, the outcomes from the (generic) CG simulation fashions can be utilized to clarify the impact of various head teams and totally different counterions on the aggregation of PE telechelics and the order of the obtained nanocrystals.

Modelling the visible response to an OUReP retinal prosthesis with photoelectric dye coupled to polyethylene movie

 Goal: Retinal prostheses have been developed to revive imaginative and prescient in blind sufferers affected by illnesses like retinitis pigmentosa.

 Method: A brand new kind of retinal prosthesis known as the Okayama College-type Retinal Prosthesis (OUReP) was developed by chemically coupling photoelectric dyes to a polyethylene movie floor. The prosthesis works by passively producing an electrical potential when stimulated by gentle. Nevertheless, the neurophysiological mechanism of how OUReP stimulates the degenerated retina is unknown.

 Fundamental outcomes: Right here, we discover how the OUReP impacts retinal tissues utilizing a finite factor mannequin to resolve for the potential contained in the tissue and an energetic Hodgkin-Huxley mannequin based mostly on rat imaginative and prescient to foretell the corresponding retinal bipolar response.

 Significance: We present that the OUReP is probably going able to eliciting responses in retinal bipolar cells essential to generate imaginative and prescient underneath most ambient circumstances.

Chitosan-Functionalized Recycled Polyethylene Terephthalate Nanofibrous Membrane for Sustainable On-Demand Oil-Water Separation

 The preservation of marine ecosystems is among the most extreme challenges at current. Particularly, oil-water separation from oil spills and oily wastewater is vital. Because of this, a low-cost, efficient, and sustainable polymeric answer is in excessive demand. On this work, a controlled-wettability membrane for selective separation of oil-water mixtures and emulsions is developed. The nanofibrous membrane is ready through a facile and cost-effective electrospinning approach utilizing environmentally sustainable supplies, corresponding to recycled polyethylene terephthalate and chitosan.

The impact of various concentrations of chitosan on the morphology, chemical composition, mechanical properties, wettability, and separation efficiency of the membrane is evaluated. The membranes exhibited underoil superhydrophobic and underwater superoleophobic conduct, which is important to carry out the selective separation. In actual fact, the designed filter has aggressive antifouling properties (oil intrusion stress > 45 kPa) and confirmed excessive heavy- and light-oil/water separation efficiencies (>95%) each for emulsions and immiscible mixtures.

In vitro bio-interaction responses and hemocompatibility of Nano-based Linear Low-Density Polyethylene Polymer Embedded with Heterogeneous TiO 2/ZnO Nanocomposites for biomedical functions

 An modern nano-base polymer that scavenges radicals and reactive oxygen species displays potential antibacterial properties, that are essential within the biomedical area, significantly in lowering nosocomial infections. Nevertheless, the security of this nano-based polymer, which has direct contact with the human system, has not been totally understood. The current research investigated the cytocompatibility and hemocompatibility responses of linear low-density polyethylene polymer (LLDPE) embedded with distinction ratios of heterogeneous TiO2/ZnO nanocomposites.

Publicity of the blood and fibroblast cells to LLDPE/100Z and LLDPE/25T75Z/10% nanocomposite movies for 48 and 72 h decreased their viability by lower than 40%, in contrast with LLDPE, LLDPE/100T and LLDPE/25T75Z/5% nanocomposite movies. It additionally offered attainable mobile harm and cytotoxicity, which was supported by the findings from the numerous launch of extracellular lactate dehydrogenase (LDH) profiles and cell survival assay Additional remark utilizing an electron microscope revealed that LLDPE movies with heterogeneous 25T75Z/5% promoted cell adhesion.

Furthermore, no hemolysis was detected in all ratios of heterogeneous TiO2/ZnO nanocomposite in LLDPE movie because it was lower than 0.2%, suggesting that these supplies had been hemocompatible. This research on LLDPE movie with heterogeneous TiO2/ZnO nanocomposites demonstrated favorable biocompatible properties that had been important for superior biomedical polymer utility in a hospital setting.

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